Throughout his career, Durham has explored various mediums, including sculpture, performance, and collage. His art serves as a critique of Western culture, often employing irony to highlight the colonizing procedures that have historically marginalized indigenous voices. This approach has placed him at the forefront of contemporary discussions on art and social justice.

The updated edition of his work by Phaidon marks a significant moment in the understanding of Durham's contribution to art. This comprehensive assessment not only traces his life experiences in the US, Mexico, and Europe but also encapsulates the evolution of his artistic output over the years.

Jimmie Durham's legacy is a testament to the power of art as a medium for change and reflection. His ability to confront uncomfortable truths through creativity continues to inspire artists and audiences alike, making his work essential for anyone interested in the intersections of art, culture, and history.